Drugs increase the level of which neurotransmitter that causes the feeling of a high?

The feeling of a "high" that individuals often associate with drug use is primarily linked to the increase in dopamine levels in the brain. Dopamine is a neurotransmitter that plays a critical role in the brain's reward system, signaling pleasure and reinforcing behaviors that are rewarding or enjoyable. Many drugs, particularly stimulants like cocaine and amphetamines, directly increase dopamine activity, leading to feelings of euphoria and pleasure.

This dopamine release triggers neural pathways that are associated with motivation, reward, and reinforcement, which contributes to the addictive properties of certain substances. Understanding the relationship between dopamine and feelings of pleasure can help in grasping the broader implications of substance use and potential addiction issues.