What does increased tolerance refer to in the context of substance use?

Increased tolerance in the context of substance use specifically refers to the phenomenon where an individual requires a larger amount of the substance to achieve the same effects that they previously experienced with a smaller dose. Over time, with continued use of a substance, the body adapts to its presence, leading to a diminished response to that substance. This means that as tolerance increases, the individual may need to consume higher quantities to reach the desired euphoric effects or relief from withdrawal symptoms.

This distinction is crucial in understanding substance use and the development of substance use disorders, as increased tolerance can often lead to escalating use and potential dependencies. It helps outline the physiological adaptations that the brain and body undergo in response to chronic exposure to psychoactive substances, which can significantly impact treatment strategies for substance use disorders.