What is a potential outcome of opiate overdose?

Opiate overdose can lead to severe central nervous system depression, which may manifest as convulsions and coma. This occurs because opiates inhibit neurotransmission and respiratory function, which can lead to a decrease in brain activity and responsiveness. As a result, an individual may become unresponsive or lose consciousness, progressing to a comatose state if the overdose is significant and not treated. Convulsions may also arise due to the body's reaction to the overwhelming level of the drug in the system, leading to agitation of the nervous system.

In contrast, the other choices reflect outcomes that are not typically associated with opiate overdose. Increased heart rate is more common with stimulants rather than depressants like opiates. Heightened sensory perception and enhanced motor skills are generally effects of stimulant drugs or can occur in moderate doses of some substances, but are not characteristic of opiate action.