Which criterion relates to failures in meeting responsibilities at work, home, or school due to substance use?

The criterion that relates to failures in meeting responsibilities at work, home, or school due to substance use is distinctly characterized as a part of substance use disorder. This condition is defined by a range of symptoms and behaviors associated with dependency on alcohol or drugs, and one of the key features is the individual's inability to fulfill major obligations due to their substance use.

Substance use disorder encompasses not just the frequency of substance use, but the negative impact it has on a person's life, including deteriorating performance in various spheres such as work or education, and neglecting household responsibilities. This multifunctional aspect of the disorder highlights the significant consequences that substance use can have on daily functioning and overall quality of life.

In contrast, terms like substance prevalence and substance conflict do not directly address the failure to meet responsibilities resulting from substance use. Substance prevalence relates to how common a specific substance is within a population, while substance conflict refers to any disputes or issues arising from substance use, neither of which inherently entails a focus on personal responsibility. Substance neglect, while it might imply a lack of care due to substance use, does not encapsulate the broader range of effects that characterize substance use disorder.